fbpx Skip to main content


Frank de Wolf, M.D., PH.D.

As Global Head of the Janssen Prevention Center, Frank de Wolf is responsible for driving research to develop new concepts for disease prevention that will extend the healthy life span. He was appointed to this position in March 2017.

Frank has been Head of Operations and Medical Affairs at the Janssen Prevention Center since its inception at the start of 2015, in which roles he has supported the research center’s operational and strategic development. He has also led the Prevention Markers platform of the Janssen Prevention Center, driving collaborative research to identify novel biomarkers of health and disease risk. The outcomes of this work will guide further research to keep people healthy and vital for life.

Frank joined Janssen at the end of 2012, after more than 25 years leading HIV/AIDS research. He entered this emerging field in 1984, initiating cohort studies that helped to elucidate the natural history of HIV/AIDS and leading the development of mathematical pathogenesis models to guide the initiation of therapy. Frank founded the Dutch HIV Monitoring Foundation in 2001 and was its Director for 11 years before joining Janssen, initially as Chief Operating Officer and Chief Medical Officer of the Crucell Vaccine Institute.

Frank holds the academic position of Professor of Clinical Retrovirology in the Department of Infectious Diseases Epidemiology, School of Public Health of Imperial College London, United Kingdom. He received M.D. and Ph.D. degrees from the University of Amsterdam, the Netherlands, and is a registered medical microbiologist.

Under Frank’s leadership, the Janssen Prevention Center will continue its efforts to explore new approaches to prevention, with a focus on preventing the non-communicable diseases that come with age.