About Psoriasis
Psoriasis (PsO) is an immune-mediated disease resulting in an overproduction of skin cells, which causes raised, red, scaly plaques that may be itchy or painful.2 It is estimated that eight million Americans and more than 125 million people worldwide live with the disease.3 Nearly one-quarter of all people with PsO have cases that are considered moderate to severe.3 Living with PsO can be a challenge and impact life beyond a person’s physical health, including emotional health, relationships, and handling the stressors of life.3 PsO is associated with multiple comorbidities, including psoriatic arthritis, metabolic syndrome, cardiovascular diseases, psychological disorders, inflammatory bowel disease, and additional immune-mediated diseases.4
About Hidradenitis Suppurativa
Hidradenitis suppurativa (HS) is a chronic disease characterized by swollen, painful lesions, occurring in the armpit (axillae), groin, anal, and breast regions of men and women.5 This progressive disease occurs due to obstruction of hair follicles and secondary infection and sometimes inflammation of certain sweat glands (apocrine glands).5,6 Healing of affected areas is typically associated with progressive scarring (fibrosis).5,6 Formation of chronic epithelialized, sometimes interconnected, sinus tracts occur in severe disease.5 This often leads to the entrapment of perspiration and bacteria in the surrounding tissue, which causes the inflammation and infection.5,6 HS can be extremely painful and debilitating but is rarely life threatening; only occurring when the bacteria infection leads to an overwhelming systemic infection in an individual with a weakened immune system.6,7,8 Although the exact cause of HS is unknown, the condition likely results from a combination of genetic and environmental factors.5
About Atopic Dermatitis
Atopic dermatitis (AD), sometimes referred to as eczema, is a chronic skin disorder affecting more than 9.6 million children and 16.5 million adults in the United States.9 AD is characterized by an overactive immune system that causes damage to the skin barrier, leaving it dry, itchy, and prone to rashes.9 AD may come and go throughout life and is considered a severe condition.9 The condition can cause poor quality of life by interrupting sleep due to itching and/or painful skin, and by impacting the ability to interact with family and friends.9