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Cardiovascular and Metabolic Diseases

Cardiovascular and Metabolic Diseases

With poor diet and lifestyle choices contributing to what are becoming critical worldwide health issues, heart disease, diabetes and obesity will continue to increase and require new approaches to prevention and treatment.

Cardiovascular and metabolic diseases are a major threat to life for adults, accounting for millions of deaths worldwide each year. Heart disease is the number one killer in both men and women. Diabetes is the fourth leading cause of death in most developed countries. At Janssen we are building a comprehensive approach to diabetes care as well as cardiovascular disease.

Janssen has an enduring commitment to researching the prevention and treatment of cardiovascular and metabolic diseases. Our aim is to develop innovative healthcare solutions that will significantly improve the outcome for patients.


Diabetes is a common long term health condition. The most recent figures highlight that in Ireland between 1980 and 2014, diabetes has become more common amongst men than women. The incidence of the disease increased from 4.3% to 7.3% for men and from 3.3% to 5.1% for women1

There are two types of diabetes: type 1 and type 2. Type 1 diabetes accounts for about 10 per cent of all adults. It typically develops in children and young adults. In type 1 diabetes, your body stops making insulin which results in blood sugar (glucose) levels becoming very high. Type 2 diabetes develops when your body can’t produce enough insulin, or when the insulin that is produced doesn’t work properly. If untreated, it can cause very serious health problems2

Type 2 diabetes, the most common form of diabetes, is a chronic condition that causes the body’s blood glucose (sugar) levels to rise higher than normal causing blood vessel damage over time, if the condition is not well controlled. It is estimated that there are over 225,000 people in Ireland with diabetes and 90% of those, or 205,000, live with type 23. The growing levels of obesity, one of the contributing factors in developing type 2 diabetes, will see this number rise to over 250,000 by 20304.

Research carried out between Diabetes Ireland and Janssen indicated that people may not be managing their condition effectively, even though they think they are. The research revealed that 70% feel they are in control of their diabetes.  However only half significantly changed their diet, just 35% significantly improved their exercise habits and almost a quarter (23%) forgot to take their diabetes medication at some stage in the previous month

In response to this survey, Janssen developed a “Take Control” Checklist in conjunction with Diabetes Ireland to guide people through simple steps that will help them take control of their condition. Click on the link below for further information.

PDF : Take control of your diabetes pdf

As part of the wider Johnson and Johnson family of companies, with a strong heritage in the area of diabetes, Janssen is committed to improving the lives of people living with type 2 diabetes. Janssen's clinical trials in this disease area have to date involved over 10,000 people and the registration trial for our recently launched medicine was the largest trial ever carried out in type 2 diabetes. We continue to invest in diabetes and have an ongoing commitment to research new treatments to address some of the most important unmet medical needs.

For more information on Diabetes Ireland please visit

  2. World Health Organisation The Top 10 Causes of Death
  3. Diabetes Ireland: Diabetes Prevalence in Ireland Accessed May 2016
  4. World Health Organization, Media Centre, Diabetes, Fact sheet Number 312. Available at: Accessed May 2016
  5. Empathy Research – postal survey of 300 Diabetes Ireland members