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Immunology Research

Immunology

We have a strong history of delivering biological medicines for immunological diseases and we continue to build a pipeline of exciting, new biotechnological products, while expanding into small-molecule oral medications and broadening our disease focus in autoimmune, inflammatory and pulmonary diseases. Through our ongoing efforts in discovery, biomarkers, clinical research and external innovation, we are poised for continued leadership and growth, bringing transformational medicines to patients and healthcare providers around the world.

Read our Janssen in immunology leaflet to learn more about our commitment to immunology.

GutcastGutcast Podcast Series

Janssen Sciences Ireland UC, in partnership with the Irish Society for Colitis and Crohn’s Disease (ISCC), is proud to launch Gutcast, the first podcast series for people living with inflammatory bowel disease (IBD) in Ireland. Gutcast brings together healthcare professionals and well-known personalities living with IBD to share insights on a range of issues such as mental health, fatigue, managing work and social life, sex and relationships and getting the most from healthcare appointments. The podcast has been launched in response to national research that highlights the extent of mental health concerns among those living with IBD and the need for accessible supports for stress, anxiety and depression, all of which are being compounded by COVID-19.

IBD is an umbrella term used to describe disorders that involve chronic inflammation of the digestive tract and include Crohn’s disease and ulcerative colitis. It is thought that at least 40,000 people in Ireland are living with IBD, most of whom are diagnosed between the ages of 15 and 35[6].

The research revealed that mental health issues have the highest impact on everyday life with 82% of people with IBD stating they have experienced stress, 74% experienced anxiety and 53% experienced depression due to their condition[7]. In response to this research, ‘Gutcast’ has been developed to provide practical advice and information for people living with IBD in a digital format that can be easily accessed. A bonus episode was recorded in response to COVID-19 to further support patients during this stressful time.

The patient voice is at the heart of Gutcast. The content was driven by patient insights and informed by the knowledge and experience of our patient group partner. Gutcast is hosted by Amy Kelly, who lives with Crohn’s and is a board member of the ISCC. Our mission with this initiative is to help people become more informed about IBD and empower them to take control of their condition which will lead to better health outcomes.

Gutcast comprises eight episodes and is available on the ISCC website as well as on Apple Podcast App, Google Play Music and Spotify.

Janssen has produced a comprehensive source of information on psoriasis  for patients called Psoriasis 360, including treatment options and practical advice to help patients reduce the physical, social and emotional impact that a long-term skin condition can have on their lives.

Psoriasis  is estimated to affect more than 73,000 people in Ireland. Anyone can develop psoriasis. It is equally common in men and women.[1]

More than Skin Deep – Psoriatic Arthritis Awareness Campaign

Janssen Ireland, supported by Arthritis Ireland, has launched the More than Skin Deep campaign to educate people about the link between psoriasis and psoriatic arthritis – an inflammatory form of arthritis that can cause pain, swelling and damage to joints.

Our research revealed that 46%[2] of people with psoriasis have never heard of psoriatic arthritis. Yet, up to 30%[3] of the estimated 73,000[4] people with psoriasis in Ireland may go on to develop the condition.

These videos – presented by Paul Walsh from RTE’s Doctors on Call – provide information from experts on psoriatic arthritis including the signs and symptoms and how it can be managed.

More than Skin Deep: Interview with Marion Morrissey, who has psoriatic arthritis, about her journey from psoriasis to psoriatic arthritis and how she manages her condition.

The Journey: Consultant Rheumatologist, Professor David Kane and Consultant Dermatologist, Dr Anne-Marie Tobin, both based in Tallaght Hospital, Dublin, talk about the link between psoriasis and psoriatic arthritis, including the signs, symptoms and how it is diagnosed.

Managing the Journey:  Professor David Kane and Dr Anne-Marie Tobin give advice on how best to manage the journey from psoriasis to psoriatic arthritis.

What is psoriatic arthritis?

Psoriatic Arthritis (PsA) is an autoimmune disease - a form of inflammatory arthritis that can cause pain, swelling and damage to any joint in the body.[5] In most cases people with PsA develop the condition following the onset of psoriasis. This does not mean that all people with psoriasis will develop PsA. Due to the similarities of symptoms it may sometimes be confused with other forms of arthritis.[5]

The symptoms of psoriatic arthritis vary from person-to-person but the main indicators include:4

  • Thickening, discoloration and pitting of the nails
  • Stiff, painful, swollen joints. Psoriatic arthritis typically affects the ankle, knees, toes and lower back
  • Sausage-like swelling of the fingers or toes
  • Tenderness or pain where tendons or ligaments attach to bones. This commonly occurs at the heel or the bottom of the foot, but it can also occur in the elbow
  • Pain and swelling at the back of the heel
  • Eye inflammation (less frequent)

 

Follow @JanssenIE and @Arthritisie to find out more. You can also log on to arthritisireland.ie or phone the Arthritis Ireland helpline on 1890 252 846 for more information.

 

iMR Code: EM-37476
Date of prep: July 2020

 

Reference


[1] Irish skin foundation : https://irishskin.ie/

[2] Empathy Research of 153 psoriasis sufferers aged 18+. 8th – 19th September 2016

[3] National Psoriasis Foundation - https://www.psoriasis.org/about-psoriatic-arthritis. Last accessed January 2016

[4] Irish Skin Foundation - https://irishskin.ie/. Last accessed January 2016

[5] Arthritis Ireland. Living with psoriatic arthritis booklet http://www.arthritisireland.ie/go/information/booklets/psoriatic_arthritis. Last accessed January 2014

[6] What is IBD. https://iscc.ie/facts/what-is-ibd/Last accessed 24 June 2020

[7] Research commissioned on behalf of Janssen in partnership with the ISCC, carried out by Freedom Consulting, on a total of 298 people with IBD. Research conducted in April 2018