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Commitment to Gastroenterology

Our Commitment to
Our Commitment to Gastroenterology

Welcome to the Janssen Immunology Gastroenterology Newsroom! Below, please find the latest on our Gastroenterology news, a message from our leaders, social feeds, and more information about our progress and commitment to developing innovative medicines for diseases such as Crohn’s disease (CD) and ulcerative colitis (UC).

Janssen’s Commitment to Gastroenterology
A Message from our Gastroenterology Disease Area Leaders

Dear All,

At Janssen Immunology, we remain steadfast in our commitment to address unmet need, uncover novel treatment approaches, and work collaboratively to deliver transformational therapies for patients with gastrointestinal (GI) diseases, including inflammatory bowel diseases (IBD) like CD and UC. We understand that significant unmet need remains in these conditions, and that many patients around the world are struggling to find the right treatment, maintain symptom relief and achieve remission. These patients are the motivating force that drives us to continue to pioneer research and achieve our vision to restore health for all patients with GI diseases.

Learn more about our research below!

Richard Appiah
Commercial Disease Area Leader
Gastroenterology and IL-23 Pathway
View Richard’s LinkedIn Profile

Jan Wehkamp, M.D.
Disease Area Leader
View Jan's LinkedIn Profile







About Crohn's Disease

CD is one of the two main forms of inflammatory bowel disease, which affects an estimated three million Americans.1 CD is a chronic inflammatory condition of the gastrointestinal tract with no known cause, but the disease is associated with abnormalities of the immune system that could be triggered by a genetic predisposition, diet or other environmental factors.2 Symptoms of CD can vary but often include abdominal pain and tenderness, frequent diarrhea, rectal bleeding, weight loss and fever.3 There is currently no cure for CD.4

About Ulcerative Colitis

More than five million people worldwide are living with CD and UC—commonly known as inflammatory bowel disease. UC affects nearly 907,000 people in the U.S., with approximately 38,000 new cases diagnosed each year.5 UC is a chronic disease of the large intestine, also known as the colon, in which the lining of the colon becomes inflamed and develops tiny open sores, or ulcers, that produce pus and mucus. It is the result of an abnormal response by the body's immune system.6 Symptoms vary but may include loose and more urgent bowel movements, persistent diarrhea, abdominal pain, bloody stool, loss of appetite, weight loss and fatigue.7

Driven by a relentless focus on patient unmet need, we will redefine treatments for immune diseases by delivering transformational and accessible therapies and regimens to patients with autoimmune disease.

Learn more:


1 Overview of Crohn’s Disease. (n.d.). Crohn’s & Colitis Foundation. Retrieved April 22, 2021, from https://www.crohnscolitisfoundation.org/what-is-crohns-disease/overview
2 Causes of Crohn’s Disease. (n.d.). Crohn’s & Colitis Foundation. Retrieved April 22, 2021, from https://www.crohnscolitisfoundation.org/what-is-crohns-disease/causes
3 Signs and Symptoms of Crohn’s Disease. (n.d.). Crohn’s & Colitis Foundation. Retrieved April 22, 2021, from https://www.crohnscolitisfoundation.org/what-is-crohns-disease/symptoms
4 Crohn’s disease - Symptoms and causes. (2020, October 13). Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/crohns-disease/symptoms-c...
5 The Facts About Inflammatory Bowel Diseases. (n.d.). Crohn’s & Colitis Foundation of America. Retrieved April 22, 2021, from https://www.crohnscolitisfoundation.org/sites/default/files/2019-02/Upda...
6 What is Ulcerative Colitis? (n.d.). Crohn’s & Colitis Foundation. Retrieved April 22, 2021, from https://www.crohnscolitisfoundation.org/what-is-ulcerative-colitis
7 Signs and Symptoms of Ulcerative Colitis. (n.d.). Crohn’s & Colitis Foundation. Retrieved April 22, 2021, from https://www.crohnscolitisfoundation.org/what-is-ulcerative-colitis/symptoms