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Discovering Neuroscience Innovation


“Our goal is to drive the types of discoveries that will ultimately improve the prevention, diagnosis and treatment of neuropsychiatric and neurodegenerative diseases for generations to come.”

David Bredt

Global Head of Discovery

Across Neuroscience, Janssen researchers are exploring the emerging science in neurodegenerative and neuroinflammatory disorders, including synaptic plasticity and cellular resilience. We also are seeking to leverage breakthrough technologies in imaging, genomics and associated biomarkers.

Recent research has linked neuronal plasticity and cellular resilience to learning, memory, cognition and mood. We know that neuropsychiatric and neurodegenerative disorders arise from abnormalities in neuronal plasticity and cellular resilience cascades.

At Janssen, we are increasingly focused in this area because understanding how to control and augment this ability for the brain and central nervous system to adapt may lead to the discovery of novel therapeutics for the treatment of severe mood disorders and neurodegenerative dementias.

Our strategy is to harness the best science in the world, whether from our own laboratories or through strategic relationships and collaborations with academia, biotech and other pharmaceutical companies.




Nerve fibers
Nerve fibers