Infectious Diseases and Vaccines
Infectious diseases and vaccines
Infectious Diseases and Vaccines is one of the areas of research at Janssen. In this field of expertise, we work on innovative solutions that contribute to the global fight against life-threatening infectious diseases. Our approach is focussed on three pillars: prevention, treatment, and cure. In this way we can improve the lives of millions of people around the world and make a difference in the lives of patients. Among other things, we are working on vaccines against the human immunodeficiency virus (HIV), hepatitis B, viral respiratory tract, bacterial infections and other infectious diseases.
What is an infectious disease?
Infectious diseases are caused by pathogenic microorganisms. These organisms, such as bacteria, viruses, parasites, or fungi, are so small that you cannot see them with the naked eye.9 How the infection with an infectious disease occurs depends on the type of infectious disease. For example, HIV can be transmitted via body fluids such as blood, semen, vaginal fluid, or breast milk.10
Infectious diseases account for 15% of all deaths worldwide each year.11 These diseases do not only occur in developing countries, but also in Belgium! For example, HIV: in 2018, the number of people living with HIV in Belgium was estimated at 19.203. That same year, 882 new HIV diagnoses were diagnosed.12
Vaccination is one of the most effective methods of preventing infectious diseases.13 It is estimated that between 2 and 3 million lives are saved each year thanks to vaccination.14 How does that work?
Vaccines train the immune system to recognise a particular pathogen. Vaccination is the introduction of a harmless part of a virus into the body. This harmless part of the virus cannot cause illness, but the immune system does react to it. By creating different types of immune cells, a long-term response against the virus is created. Vaccination ensures that the immune system remembers the virus. When in the future the real virus enters the body, the body can react fast and effective, preventing illness.
At Janssen, we devote a great deal of attention to research into infectious diseases, the development of medicines, and vaccines against these diseases. We do this from several centres of expertise, including Janssen in Beerse and Janssen Vaccines in Leiden. At the Janssen Beerse site in Belgium, the focus lies on various activities: from the discovery and development of new medicines against infectious diseases, to pharmaceutical production.
We develop our vaccines from our facilities at Janssen Vaccines in Leiden (the Netherlands). Here we investigate vaccines against various infectious diseases, such as respiratory syncytic virus (RSV), HIV, Extra-intestinal Pathogenic E. coli (ExPEC) and Methicillin-Resistant Staphylococcus aureus (MRSA) and COVID-19. Our vaccine against Ebola has been approved by the European Medicines Agency (EMA).
Some of our vaccines make use of our vaccine technology platform AdVac®.
Our achievements in the field of Infectious Diseases & Vaccines
Together we are taking steps forward, contributing to the prevention of life-threatening infectious diseases and creating a better world: today and for tomorrow! We are proud of the results we have achieved so far. We have also contributed to this in Belgium and the Netherlands:
• One of our tuberculosis medicines (discovered and developed in Belgium) is included in the list of essential medicines of the World Health Organisation (WHO).
• For the screening of therapies against COVID-19, Janssen in Belgium collaborates with the Rega Institute for Medical Research (KU Leuven).
• Our PCR-tests (polymerase chain reaction) in the Janssen laboratories in Beerse (Belgium) are used to investigate whether someone is infected with the coronavirus.
• More than 100 colleagues (most of them working on our site in Leiden) contribute to our scientific response to COVID-19. To this end, we collaborate with the Department of Medical Microbiology of Leiden University Medical Centre.
More information about Janssen
Read more about our vaccine activities and our other areas of expertise. You can also learn more about the activities of Janssen Belgium and what working at Janssen looks like. You can also follow us via social media on Twitter, Facebook and LinkedIn to stay up to date with the latest developments.
9 World Health Organisation. Health topics - Infectious diseases. Available at: https://www.who.int/topics/infectious_diseases/en/. Last accessed: August 2020.
10 Centers for Disease Control and Prevention. HIV – Transmission. Available at: https://www.cdc.gov/hiv/basics/transmission.html. Last accessed: August 2020.
11 World Health Organisation. Projections of mortality and causes of death, 2016 to 2060 – Global summary projections. Available at: https://www.who.int/healthinfo/global_burden_disease/projections/en/. Last accessed: August 2020.
12 Sciensano, 2019. Epidemiologie Van Aids En HIV-Infectie In België - Toestand Op 31 December 2018. Brussel: Dr Myriam Sneyers. Available at: https://doi.org/10.25608/5c9n-4t26. Last Accessed: 5 November 2020.
13 World Health Organisation. Ten years in public health 2007-2017 - The power of vaccines: still not fully utilized. Available at: https://www.who.int/publications/10-year-review/en/. Last accessed: August 2020.
14 World Health Organisation. Immunization. Available at: https://www.who.int/news-room/facts-in-pictures/detail/immunization. Last accessed: August 2020.
EM-43146 - 01-okt-2020